RNA Details
Disease Name
viral myocarditis
Tissue
heart
RNA Symbol
miR-30a-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
RT-PCR;western blot;dual luciferase reporter assay etc.
Target
SOCS1
Pathway
NA
PubMed ID
Title
MicroRNA-30a-5p silencing polarizes macrophages toward M2 phenotype to alleviate cardiac injury following viral myocarditis by targeting SOCS1
Year
2021
Function
Silencing of miR-30a-5p may promote M2 polarization of macrophages and improve cardiac injury following viral myocarditis (VMC) via SOCS1 upregulation.